AceSedate can be used in dogs and cats for:
- Anaesthetic premedication – following premedication with acepromazine, the dose of anaesthetic induction agent required may be reduced by approximately one-third.
- Tranquilisation – at low doses, acepromazine provides tranquilisation/anxiolysis that are not associated with hypnosis, narcosis or marked sedation
- Sedation - at a high dose, acepromazine results in sedation. Sedation plateaus at higher doses.
- Signs of sedation will normally appear after 30 to 40 minutes following intramuscular administration and 10 to 15 minutes after intravenous injection.
- Sedative effects will last for approximately 6 hours and are not antagonisable.
- Combining AceSedate with an opioid (neuroleptanalgesia) will improve the quality and reliability of sedation and provide analgesia.1,2,3
- As with most sedative agents, to ensure maximal sedative effect, quiet handling and minimal stimulation are required following administration to reduce the possibility of arousal or excitement.
- Monitor and maintain the patient’s body temperature following acepromazine administration.
- Some Boxer dogs may be sensitive to acepromazine – a dose below or equal to 0.01 mg/kg is recommended.1
- Acepromazine is a mild anti-histamine and this effect should be considered when selecting a premedicant/sedative prior to intradermal allergy testing.1
- Murrell J (2016). Pre-anaesthetic medication and sedation. BSAVA Manual of Canine & Feline Anaesthesia & Analgesia. 3rd Edition.
- Dugdale A (2010). Veterinary Anaesthesia: Principles to Practice.
- Murrell J (2007). Choice of premedicants in cats and dogs. In Practice 29, 100-106.
|Premedication||0.03 - 0.125 mg/kg||Subcutaneous or slow intravenous injection|
|Other uses||0.0625 - 0.125 mg/kg||Intramuscular, subcutaneous or slow intravenous injection|